Synthetic cannabinoids (called spice, K2, and other names) are man-made chemicals and, despite the name, are not marijuana or cannabinoid medicines.20 Synthetic cannabinoids are often sprayed onto dried plant material that can then be smoked or sold as liquids to use in vaping devices.
Synthetic cannabinoids are part of a group of unregulated, mind-altering drugs that attempt to produce effects similar to illicit drugs. Their effects are not fully understood and can cause dangerous and unpredictable health effects because of their unpredictable chemical contents.21 Once these products are identified in the illegal marketplace, they are added to the list of schedule I substances by the Drug Enforcement Administration. Schedule I substances are illegal throughout the United States and are defined as having no medical use and high potential for abuse.
Synthetic cannabinoids can affect the brain much more powerfully than marijuana, creating unpredictable and, in some cases, life-threatening effects, including:
nausea
anxiety
paranoia
brain swelling
seizures
hallucinations
aggression
heart palpitations
chest pains
Cases of severe injury and death from use of synthetic cannabinoids have been reported, along with regional outbreaks when a contaminated batch enters a specific community.22 For additional questions around synthetic cannabinoids, visit CDC’s National Center for Environmental Health page on synthetic marijuana or the National Institute on Drug Abuse page on synthetic cannabinoids.
If someone you know has used synthetic cannabinoids and needs help, you can take the following steps:
Call 911 immediately if someone stops breathing, collapses, or has a seizure. These symptoms can be life-threatening and require immediate medical attention.
Call your local poison control center at 1-800-222-1222.
Call your doctor.